IGF-1 LR3 Peptide – Long-Acting IGF Research Compound

IGF-1 LR3 (Insulin-Like Growth Factor-1 Long Arg3) is a modified analog of IGF-1 widely studied in cellular growth signaling, protein synthesis pathways, and receptor-binding research models. Due to its structural modification and extended activity profile in laboratory environments, IGF-1 LR3 has become a commonly referenced compound in molecular biology and metabolic signaling studies.

Designed for research applications, this peptide is utilized in controlled experimental settings investigating cellular proliferation, pathway activation, and peptide-receptor interaction mechanisms.

What Is IGF-1 LR3?

IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 engineered with an arginine substitution and extended amino sequence. In research contexts, these modifications are studied for their effect on:

• Receptor binding affinity

• Signal transduction pathways

• Cellular growth regulation

• Metabolic signaling cascades

Because of these characteristics, IGF-1 LR3 is frequently selected for laboratory studies focused on growth factor signaling dynamics and protein pathway analysis.

Typical Research Dosing Ranges

Preparation & Storage (Research Protocols)

• Reconstitution: A 1 mg vial is often mixed with 3 mL bacteriostatic water → ~333 mcg/mL concentration.
• Measuring: On a U‑100 insulin syringe, 1 unit ≈ 3.33 mcg.
• Storage:
  • Lyophilized powder: −20 °C for up to 12 months.
  • After reconstitution: Refrigerate at 2–8 °C, use within 30 days, avoid repeated freeze–thaw cycles.

Key Considerations & Risks

• Blood sugar fluctuations: IGF‑1 LR3 can affect glucose metabolism.
• Potential side effects: Hypoglycemia, joint pain, organ enlargement, and other systemic effects have been noted in research.
• Legal/ethical status: It is not approved for therapeutic use in humans; possession or use outside research may be illegal depending on jurisdiction.

⚠️ Important: If you are asking about IGF‑1 LR3 for personal use, please be cautious. This compound is experimental, unregulated, and potentially dangerous outside controlled laboratory settings. For any health or performance goals, it’s far safer to consult a licensed medical professional about approved treatments or supplements.

Would you like me to break down how IGF‑1 LR3 compares to native IGF‑1 in terms of half‑life and activity? That might give you a clearer picture of why researchers use LR3 instead of the natural form.

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) – 1 MG

IGF-1 LR3 is a synthetic analog of human IGF-1 modified with an arginine substitution at position 3 and a 13-amino acid extension at the N-terminus. These changes dramatically reduce IGF binding protein affinity, increasing biological half-life. It’s studied for its roles in cellular growth, muscle hypertrophy, and metabolic signaling.

Key Features:

•  High-purity IGF-1 analog with extended half-life
•  Lyophilized powder for reliable storage and handling
•  QC verified for sequence integrity

Product Details:

• Contents: 1 MG IGF-1 LR3 peptide
• Appearance: White to off-white lyophilized powder
• Formula: C₄₀₀H₆₂₅N₁₁₁O₁₂₀S₉
• M.W.: ~9117.5 g/mol
• CAS #: 946870-92-4
• Intended Use: For laboratory research use only