Mazdutide peptide is an investigational peptide studied at the bench for receptor pharmacology, analytical method development, and in-vitro characterization. This material is supplied for research use only and is not approved for any medical use.
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Description
Mazdutide Peptide – Advanced Incretin Therapy for Metabolic Health
Mazdutide is a next‑generation investigational peptide designed to target multiple hormone receptors involved in metabolic regulation. As part of the evolving class of incretin‑based therapies, Mazdutide shows promise in weight management, glucose control, and liver fat reduction. While still under clinical investigation, it is gaining attention as a potential breakthrough in obesity and type 2 diabetes treatment.
Mazdutide Peptide Benefits
- Weight Loss Support: Early trials demonstrate significant reductions in body weight.
- Improved Glucose Control: Enhances insulin sensitivity and lowers blood sugar levels.
- Lipid Profile Improvement: Positive effects on cholesterol and triglycerides.
- Liver Health: Reduction in liver fat, supporting metabolic wellness.
- Multi‑Receptor Action: Engages GLP‑1, GIP, and glucagon pathways for comprehensive metabolic regulation.
Mazdutide Dosing & Dosage
- Clinical Trials: Dosing protocols vary, but Mazdutide peptide is typically administered via injection in controlled research settings.
- Investigational Status: No standardized or FDA‑approved dosage exists yet; all usage remains experimental.
- Safety Monitoring: Trials emphasize careful titration to minimize gastrointestinal side effects and monitor metabolic responses.
Mazdutide vs Retatrutide
| Feature | Mazdutide | Retatrutide |
|---|---|---|
| Mechanism | Multi‑receptor agonist (GLP‑1, GIP, glucagon) | Triple receptor agonist (GLP‑1, GIP, glucagon) |
| Focus | Weight loss, glucose control, liver fat reduction | Broader metabolic regulation, appetite suppression, energy expenditure |
| Clinical Status | Investigational | Investigational |
| Key Difference | Balanced receptor activity | Stronger glucagon receptor engagement |
Mazdutide vs Tirzepatide
| Feature | Mazdutide | Tirzepatide |
|---|---|---|
| Mechanism | GLP‑1, GIP, glucagon agonist | Dual agonist (GLP‑1 + GIP) |
| Benefits | Weight loss, glucose control, liver fat reduction | FDA‑approved for type 2 diabetes and obesity |
| Clinical Status | Investigational | Approved and widely prescribed |
| Key Difference | Adds glucagon receptor activity for enhanced metabolic impact | Focuses on GLP‑1 and GIP pathways |
Why Mazdutide Stands Out
Mazdutide peptide represents the next evolution in incretin therapy, offering a broader receptor profile than Tirzepatide and a distinct balance compared to Retatrutide. Its potential to address obesity, diabetes, and liver health simultaneously makes it one of the most closely watched peptides in modern metabolic research.
Mazdutide peptide is an investigational peptide studied at the bench for receptor pharmacology, analytical method development, and in-vitro characterization. This material is supplied for research use only and is not approved for any medical use.
| Form |
Lyophilized powder in 3 mL glass vial |
|---|---|
| Application |
Research peptide for studies of dual GLP-1 receptor / glucagon receptor (GLP-1R/GCGR) agonism in metabolic biology |
| Appearance |
Solid, white to off-white lyophilized powder |
| Chemical Formula |
C₂₁₀H₃₂₂N₄₆O₆₇ |
| PubChem CID |
167312357 |
| CAS Number |
2259884-03-0 |
| Molecular Weight |
≈ 4,563.1 g/mol |
| Synonyms |
IBI-362; IBI362; LY-3305677; LY3305677 |
| Storage |
Keep sealed, protected from light and moisture. Lyophilized: ≤ −20 °C for long-term (or 2–8 °C short-term). After reconstitution: 2–8 °C; avoid repeated freeze–thaw; use sterile technique in research workflows. |
